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News & Research Highlights
10 April 2017: A Guinea Pig Model of Zika Virus Infection

Animal models are critical to understand the transmission and pathogenesis of infectious diseases and to develop countermeasures for their prevention and spread. Here, we report that immunocompetent Dunkin Hartley guinea pigs are susceptible to infection by a contemporary American strain of Zika vir…

30 March 2017: COBRE Small Grants Program

The purpose of the Centers of Biomedical Research Excellence (COBRE) Small Grants Program is to provide support via three funding mechanisms to University of Hawaii (UH) faculty engaged in research in tropical medicine, medical microbiology, immunology, and/or emerging infectious diseases. However, …

05 January 2017: Installation of bioBUBBLE

An instrument-dedicated, BSL-2+-certified, aerosol-management system has been installed to isolate the BD FACSAria IIu Flow Cytometer from other instrumentation within the Molecular and Cellular Immunology Core. This customized bioBUBBLE enclosure, which is retrofitted with a dedicated ventilation s…

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Recent Publications
Toxins (Basel), 2017, Evaluation of Cyanea capillata sting management protocols using ex vivo and in vitro envenomation models.
Doyle TK, Headlam JL, Wilcox CL, MacLoughlin E, Yanagihara AA.

Lion’s mane jellyfish (Cyanea capillata) stings cause severe pain and can lead to dangerous systemic effects, including Irukandji-like syndrome. As is the case for most cnidarian stings, recommended medical protocols in response to such stings lack rigorous scientific support. In this study, we soug…

Toxins (Basel), 2017, Assessing the efficacy of first aid measures in Physalia sp. envenomation, using solution- and blood agarose-based models.
Wilcox CL, Headlam JL Doyle TK, Yanagihara AA.

Stings from the hydrozoan species in the genus Physalia cause intense, immediate skin pain
and elicit serious systemic effects. There has been much scientific debate about the most appropriate first aid for these stings, particularly with regard to whether vinegar use is appropriate (most current r…

Molecular Phylogenetics and Evolution, 2017, Coral hybridization or phenotypic variation? Genomic data reveal gene flow between Porites lobata and P. compressa.
Forsman ZH, Knapp ISS, Tisthammer K, Eaton DAR, Belcaid M, Toonen RJ.

Major gaps remain in our understanding of the ecology, evolution, biodiversity, biogeography, extinction risk, and adaptive potential of reef building corals. One of the central challenges remains that there are few informative genetic markers for studying boundaries between species, and variation w…

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Seminars & Events
02 June 2017, 12:00 PM - 1:00 PM
Yi Pan, Ph.D.

Deep Learning for Bioinformatics Applications

15 May 2017, 12:00 PM - 1:00 PM
Rose Gana Fomban Leke, Ph.D.

A Personal Journey in Global Health: Eradication of Polio and Malaria

20 April 2017, 2:00 PM - 4:00 PM
David A. Relman, M.D., Victoria Fan, Sc.D., Vivek R. Nerurkar, Ph.D., Richard J. Kuhn, Ph.D.

2017 COBRE Mini-symposium

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21 October 2016, 10:00 AM
Alexandra Gurary, Ph.D.

Attune Nxt Training

20 October 2016, 03:30 PM
Alexandra Gurary, Ph.D.

Luminex Acquisition Software Training

20 October 2016, 10:00 AM
Alexandra Gurary, Ph.D.

Attune Nxt Training

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Recent Grants
NIH/NIAID, R01AI132323 Preclinical Development of a Thermostable Trivalent Filovirus Vaccine
06/20/2017 - 05/31/2022
NIH/NIDDK, 2R25DK078386-11 Pacific High Schools STEP-UP to Biomedical Research
03/01/2017 - 02/28/2022
NIH/NIAID, R21AI129465 Under Attack: Modulation of the Blood-Testes Barrier by Zika Virus
11/08/2016 - 10/31/2018
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