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News & Research Highlights
12 October 2021: Research predicting transmissible COVID-19 variants receives $780K

Hawaii, a prime tourism destination, in combination with its largely multi-racial resident population, presents a unique opportunity to identify and chart the distribution of SARS-CoV-2 variants, the virus that causes the coronavirus disease. The National Institutes of Health has committed $779,792 …

24 September 2021: $2M for mentorships help Manoa students pursue biomedical research

A federal initiative seeking to recruit and mentor STEM students from underrepresented backgrounds toward pursuing careers in biomedical research has awarded the University of Hawaii at Manoa a five-year, $2 million grant.

The National Institutes of Health’s "Maximizing Access to Research Car…

17 November 2020: RADx-UP Adminiistrative Supplement

Funding from the RADx Underserved Populations (RADx-UP) program of the Rapid Acceleration of Diagnostics (RADx) initiative, of the National Institutes of Health, will support the Puipuia le Ola project, which seeks to develop, disseminate and evaluate culturally tailored and linguistically appropria…

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Recent Publications
Clinical Infectious Diseases, 2020, Risk factors associated with clinical outcomes in 323 COVID-19 hospitalized patients in Wuhan, China
Hu L, Chen S, Fu Y, Gao Z, Long H, Wang J, Ren H, Zuo Y, Li H, Xu Q, Yu W, Liu J, Shao C, Hao J, Wang C, Ma Y, Wang Z, Yanagihara R, Deng Y.

Background: With evidence of sustained transmission in more than 190 countries, coronavirus disease 2019 (COVID-19) has been declared a global pandemic. Data are urgently needed about risk factors associated with clinical outcomes.

Methods: A retrospective review of 323 hospitalized patients with…

Frontiers in Cellular and Infection Microbiology, 2020, Reassortment between divergent strains of Camp Ripley virus (Hantaviridae) in the northern short-tailed shrew (Blarina brevicauda)
Liphardt SW, Kang HJ, Arai S, Gu SH, Cook JA, Yanagihara R

Genomic reassortment of segmented RNA virus strains is an important evolutionary mechanism that can generate novel viruses with profound effects on human and animal health, such as the H1N1 influenza pandemic in 2009 arising from reassortment of two swine influenza viruses. Reassortment is not restr…

Viruses, 2019, Highly divergent genetic variants of soricid-borne Altai virus (Hantaviridae) in Eurasia suggest ancient host-switching events.
Kang HJ, Gu SH, Yashina LN, Cook JA, Yanagihara R.

With the recent discovery of genetically distinct hantaviruses (family Hantaviridae) in shrews (order Eulipotyphla, family Soricidae), the once-conventional view that rodents (order Rodentia) served as the primordial reservoir hosts now appears improbable. The newly identified soricid-borne hantavir…

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Seminars & Events
17 November 2021, 12:00 PM - 1:00 PM
Tim Brown, Ph.D.

“The answer, my friend, is blowin’ in the wind” Failures in public health policy and messaging during the COVID-19 pandemic (TRMD 690 seminar)

20 October 2021, 12:00 PM - 1:00 PM
Richard Yanagihara, MD, MPH, Professor, Dept of Pediatrics; Angela U Sy, DrPH, Assistant Professor, Dept of Tropical Medicine, Medical Microbiology & Pharmacology (TMMMP); Wei-Kung Wang, MD, ScD, Professor, Dept of TMMMP

Partnerships in Academic and Community COVID-19 Testing Research - Puipuia le Ola: Increasing reach and uptake of COVID-19 testing among Pacific Islanders in Hawaii and Guam (TRMD 690 Seminar)

13 October 2021, 12:00 PM - 1:00 PM
Dennis Grab, Ph.D.

African Trypanosomes and the Human Blood-Brain Barrier: Insights and Revelations and with a bonus side-track to Dengue (TRMD 690 seminar)

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06 June 2019, 10:00 AM
Lisa Bellemare


15 February 2019, 9:00 AM - 12:00 PM
Drs. Youping Deng, Mark Menor & Vedbar Khadka

Genome Assembly, Evaluation and Visualization

17 October 2018, 11:00 AM
Bela Desai, Ph.D.

Improving Protein Detection: Accurate, High-Sensitivity and High-Throughput Analysis of Biomarkers

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Recent Grants
NIH / NIAID, 1R01AI149502-01 Multiplex Serodiagnostic Assays for Pathogenic Arboviruses in Brazil
06/05/2020 - 05/31/2024
Centers for Disease Control, 1 U01GH002256-01 Epidemiology and Immunity to Ebola Virus and Other Emerging Viral Infections in Liberia
09/30/2019 - 09/29/2024
NIH/FIC, 1D71TW010434-01A1 Sustainable Research Training and Capacity Building in Liberia for Emerging Viral Epidemics
09/08/2017 - 08/31/2019
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