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News & Research Highlights
05 January 2017: Installation of bioBUBBLE
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An instrument-dedicated, BSL-2+-certified, aerosol-management system has been installed to isolate the BD FACSAria IIu Flow Cytometer from other instrumentation within the Molecular and Cellular Immunology Core. This customized bioBUBBLE enclosure, which is retrofitted with a dedicated ventilation s…


02 December 2016: How Zika Virus Spreads through Sex

A worrisome mode of Zika virus (ZIKV) transmission is through unprotected sexual intercourse. COBRE Investigator, Saguna Verma, Ph.D., an associate professor of tropical medicine with the John A. Burns School of Medicine, has received the first ZIKV-response NIH funding in Hawaii to investigate how …


08 November 2016: Another New NIH Grant

COBRE Investigator, Saguna Verma, Ph.D., an associate professor in the Department of Tropical Medicine, Medical Microbiology and Pharmacology, has been awarded an R21 grant from the National Institute of Allergy and Infectious Diseases for an exploratory project aimed at understanding how Zika virus…


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Recent Publications
PLoS Neglected Tropical Diseases, 2017, Biospecimen repositories and integrated databases as critical infrastructure for pathogen discovery and pathobiology research.
Dunnum JL, Yanagihara R, Johnson KM, Armien B, Batsaikhan N, Morgan L, Cook JA.

Field collections of natural history specimens often arise through dynamic collaborations that are capable of producing a diverse array of preparations and associated data (e.g., ultra-frozen tissue, cell suspensions, feces, and endo- and ecto-parasites) with precise spatial and temporal stamps that…


Hawaii Journal of Medicine and Public Health, 2017, Pacific Center for Emerging Infectious Diseases Research.
Yanagihara R, Nerurkar VR, Hui G, Jacobs GA.

New, emerging and re-emerging infectious diseases are among the most urgent public health threats and economic challenges facing global communities in the new millennium. Recent examples of outbreaks include the emergence and rapid spread of Ebola virus disease in Guinea, Liberia and Sierra Leone; M…


Acta Medica Kindai University, 2016, Neuropathogenesis of Zika virus infection: Potential role of antibody-mediated pathology.
Tsunoda I, Omura S, Sato F, Kusunoki S, Fujita M, Park A-M, Hasanovic F, Yanagihara R, Nagata S.

Zika virus (ZIKV) is an enveloped,positive-sense, single-stranded RNA virus that belongs to the genus Flavivirus, family Flaviviridae, which includes many human and animal pathogens, such as dengue virus (DENV), West Nile virus, and Japanese encephalitis virus. In the original as well as subsequent …


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Seminars & Events
10 February 2017, 9:00 AM - 10:00 AM
Jerris R. Hedges, MD, MS, MMM
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Informational Session on the National Academy of Medicine (NAM) Nomination and Election Process


01 February 2017, 12:00 PM - 1:00 PM
Catherine M. Pirkle, Ph.D.
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Importance of Building Research Capacity for Health in Disadvantaged Global Settings


18 January 2017, 12:00 PM - 1:00 PM
Sladjana Prisic, Ph.D.
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Role of Zinc in Tuberculosis


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Workshops
21 October 2016, 10:00 AM
Alexandra Gurary, Ph.D.

Attune Nxt Training


20 October 2016, 03:30 PM
Alexandra Gurary, Ph.D.

Luminex Acquisition Software Training


20 October 2016, 10:00 AM
Alexandra Gurary, Ph.D.

Attune Nxt Training


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Recent Grants
NIH/NIAID, R21AI129465 Under Attack: Modulation of the Blood-Testes Barrier by Zika Virus
11/08/2016 - 10/31/2018
NIH/NINDS, R21NS099838 Defining the Function of Schlafen4 in the Pathogenesis of Flavivirus Encephalitis
09/01/2016 - 08/31/2018
NIH/NIEHS, R21ES027230 Pathogenesis of Life Threatening Box Jellyfish Envenomation and Irukandji Syndrome
09/01/2016 - 08/31/2018
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