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News & Research Highlights
10 April 2017: A Guinea Pig Model of Zika Virus Infection
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Animal models are critical to understand the transmission and pathogenesis of infectious diseases and to develop countermeasures for their prevention and spread. Here, we report that immunocompetent Dunkin Hartley guinea pigs are susceptible to infection by a contemporary American strain of Zika vir…


30 March 2017: COBRE Small Grants Program

The purpose of the Centers of Biomedical Research Excellence (COBRE) Small Grants Program is to provide support via three funding mechanisms to University of Hawaii (UH) faculty engaged in research in tropical medicine, medical microbiology, immunology, and/or emerging infectious diseases. However, …


05 January 2017: Installation of bioBUBBLE
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An instrument-dedicated, BSL-2+-certified, aerosol-management system has been installed to isolate the BD FACSAria IIu Flow Cytometer from other instrumentation within the Molecular and Cellular Immunology Core. This customized bioBUBBLE enclosure, which is retrofitted with a dedicated ventilation s…


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Recent Publications
Virology Journal, 2017, A guinea pig model of Zika virus infection.
Kumar M, Krause KK, Azouz F, Nakano E, Nerurkar VR.

Background: Animal models are critical to understand disease and to develop countermeasures for the ongoing epidemic of Zika virus (ZIKV). Here we report that immunocompetent guinea pigs are susceptible to infection by a contemporary American strain of ZIKV.
Methods: Dunkin-Hartley guinea pigs were…


Toxins, 2017, Cubozoan sting-site seawater rinse, scraping, and ice can increase venom load: Upending current first aid recommendations.
Yanagihara AA, Wilcox CL

Cnidarian envenomations are the leading cause of severe and lethal human sting injuries from marine life. The total amount of venom discharged into sting-site tissues, sometimes referred to as “venom load”, has been previously shown to correlate with tentacle contact length and sequelae severity. Si…


PLoS Neglected Tropical Diseases, 2017, Biospecimen repositories and integrated databases as critical infrastructure for pathogen discovery and pathobiology research.
Dunnum JL, Yanagihara R, Johnson KM, Armien B, Batsaikhan N, Morgan L, Cook JA.

Field collections of natural history specimens often arise through dynamic collaborations that are capable of producing a diverse array of preparations and associated data (e.g., ultra-frozen tissue, cell suspensions, feces, and endo- and ecto-parasites) with precise spatial and temporal stamps that…


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Seminars & Events
20 April 2017, 2:00 PM - 4:00 PM
David A. Relman, M.D., Victoria Fan, Sc.D., Vivek R. Nerurkar, Ph.D., Richard J. Kuhn, Ph.D.
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2017 COBRE Mini-symposium


02 March 2017, 9:00 AM - 10:00 AM
Howard E. Gendelman, M.D.
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LASER ART


10 February 2017, 9:00 AM - 10:00 AM
Jerris R. Hedges, MD, MS, MMM
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Informational Session on the National Academy of Medicine (NAM) Nomination and Election Process


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Workshops
21 October 2016, 10:00 AM
Alexandra Gurary, Ph.D.

Attune Nxt Training


20 October 2016, 03:30 PM
Alexandra Gurary, Ph.D.

Luminex Acquisition Software Training


20 October 2016, 10:00 AM
Alexandra Gurary, Ph.D.

Attune Nxt Training


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Recent Grants
NIH/NIDDK, 2R25DK078386-11 Pacific High Schools STEP-UP to Biomedical Research
03/01/2017 - 02/28/2022
NIH/NIAID, R21AI129465 Under Attack: Modulation of the Blood-Testes Barrier by Zika Virus
11/08/2016 - 10/31/2018
NIH/NINDS, R21NS099838 Defining the Function of Schlafen4 in the Pathogenesis of Flavivirus Encephalitis
09/01/2016 - 08/31/2018
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