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News & Research Highlights
23 August 2016: Leveraging of Small Grants Program Funding

Support from the COBRE Small Grants Program to two investigators has been successfully leveraged into NIH awards.

1R21NS099838-01 (Mukesh Kumar, Ph.D.)
Defining the Function of Schlafen4 in the Pathogenesis of Flavivirus Encephalitis
Members of the Flavivirus genus are leading causes of epi…

16 August 2016: First Hantavirus in a Fruit Bat

More than 25 genetically distinct hantaviruses have been discovered in shrews and moles (order Eulipotyphla) in Eurasia, Africa and North America. More recently, divergent lineages of hantaviruses have been detected in insectivorous bats (order Chiroptera). Because some of these hantavirus-infected …

18 July 2016: Heat-stable Ebola Vaccine

Soligenix, Inc. (OTCQB: SNGX), a late-stage biopharmaceutical company focused on developing and commercializing products to treat rare diseases where there is an unmet medical need, announced today positive preliminary proof-of-concept results from its collaboration with Axel Lehrer, Ph.D., an Assis…

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Recent Publications
Infection Genetics and Evolution, 2016, Molecular phylogeny of a genetically divergent hantavirus harbored by the Geoffroy's rousette (Rousettus amplexicaudatus), a frugivorous bat species in the Philippines.
Arai S, Taniguchi S, Aoki K, Yoshikawa Y, Kyuwa S, Tanaka-Taya K, Masangkay JS, Omatsu T, Puentespina R, Watanabe S, Alviola P, Alvarez J, Eres E, Cosico E, Quibod MN, Morikawa S, Yanagihara R, Oishi K.

The recent discovery of genetically distinct hantaviruses in multiple species of shrews and moles (order Eulipotyphla, families Soricidae and Talpidae) prompted a further exploration of their host diversification and geographic distribution by analyzing lung tissues from 376 fruit bats representing …

Tropical Medicine and Health, 2016, Dahonggou Creek virus, a divergent lineage of hantavirus harbored by the long-tailed mole (Scaptonyx fusicaudus).
Kang HJ, Gu SH, Cook JA, Yanagihara R.

Novel hantaviruses, recently detected in moles (order Eulipotyphla, family Talpidae) from Europe, Asia, and North America would predict a broader host range and wider ecological diversity. Employing RT-PCR, archival frozen tissues from the Chinese shrew mole (Uropsilus soricipes), broad-footed mole …

Toxins (Basel), 2016, Experimental assays to assess the efficacy of vinegar and other topical first-aid approaches on cubozoan (Alatina alata) tentacle firing and venom toxicity.
Yanagihara AA, Wilcox C, King R, Hurwitz K, Castelfranco AM.

Despite the medical urgency presented by cubozoan envenomations, ineffective and contradictory first-aid management recommendations persist. A critical barrier to progress has been the lack of readily available and reproducible envenomation assays that (1) recapitulate live-tentacle stings; (2) allo…

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Seminars & Events
23 August 2016, 12:00 PM - 1:00 PM
Ralph M. Garruto, Ph.D.

Modeling Reservoir, Vector, Spatial and Human Behavioral Risk of Lyme Disease in Fragmented Ecospaces within Built Environments

28 July 2016, 10:15 AM - 11:15 AM
Kim Sears, R.N., Ph.D.

From an Idea to the Delivery of an Online Graduate Program: A Five-Year Journey

29 June 2016, 11:00 AM - 12:00 PM
Pramila Walpita, Ph.D.

Mammalian Cell-derived Virus-like Particle (VLP) Vaccine Platform

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09 September 2016, 9:00 AM - 1:00 PM
Mr. Kirill Vinnikov

An Introduction to Molecular Phylogenetic Inference

29 June 2016, 12:00 PM
Lisa Bellemare, Ph.D.

Multicolor Flow Cytometer Seminar: Optimizing Performance and Experimental Design for Multicolor Panel

01 March 2016, 10:00 AM
Robert Durruthy-Durruthy, Ph.D.

Molecular and Cellular Immunology Core and Fluidigm Corporation Seminar: Single Cell Genomics Cutting Edge Microfluidic Tools Defy the Law of Averages by Enabling Resolution at the Single Cell Level

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Recent Grants
NIH/NIAID, R01AI119185 Defining a Protective Ebola Vaccine in Non-human Primates
08/28/2015 - 07/31/2019
Hawaii Community Foundation, 15ADVC-75878 West Nile Virus NS2B-NS3 Heterodimer as a Potential Target for Antiviral Drug Development
07/15/2015 - 01/14/2017
Department of Defense, U.S. Army Medical Research Acquisitions Administration, W81XWH-15-R-0015 US Army Medical Research Institute of Infectious Diseases (USAMRIID) Requirement to Develop, Produce and Deploy MAGPIX-Based Immunoassays
07/13/2015 - 07/12/2017
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