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News & Research Highlights
23 October 2015: Awardees of the 2015 COBRE Small Grants Program

Bridging support and pilot funding have been awarded to four highly meritorious proposals, submitted in response to the COBRE Small Grants Program funding opportunity announcement (FOA). The awardees are:

Sandra P. Chang, Ph.D. (Notch Signaling during Human B-cell Development and Activation)

29 July 2015: COBRE Small Grants Program

APPLICATION DUE DATE: August 21, 2015 at 4:00 p.m. (Hawaii time)
SCIENTIFIC REVIEW PERIOD: August to September 2015

University of Hawaii (UH) faculty engaged in research in microbiology, immunology, infectious diseases and tropical medicine a…

27 May 2015: Hantavirus in the Northern Red-backed Vole

Genetic evidence is provided for the first time that Hokkaido virus (HOKV) is harbored by both the grey red-backed vole (Myodes rufocanus) and northern red-backed vole (Myodes rutilus) in Siberian Russia. That HOKV was found irrespective of whether the dominant Myodes species was M. rutilus (Teletsk…

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Recent Publications
Sexually Transmitted Diseases, 2015, Molecular genotyping of human papillomavirus l1 gene in low-risk and high-risk populations in Bangkok.
Leaungwutiwong P, Bamrungsak B, Jittmittraphap A, Maneekan P, Kosoltanapiwat N, Kalambaheti T, Kelley JF.

High- and low-risk HPV genotypes persist in high-risk groups in Bangkok. Some genotypes infecting at-risk populations are not vaccine preventable. These findings may help to elucidate the prevalence of HPV infections in Thailand and serve as the basis for additional investigations into risk factors …

Oncotarget, 2015, Insights into the role of immunosenescence during varicella zoster virus infection (shingles) in the aging cell model.
Kim JA, Park SK, Kumar M, Lee CH, Shin OS.

Varicella zoster virus (VZV) is the etiological agent of shingles, a painful skin rash that affects a significant proportion of the elderly population. In the present study, we used two aging cell models, Hutchinson-Gilford progeria syndrome (HGPS) fibroblasts and stress or replicative senescence-in…

Journal of Neuroinflammation, 2015, Induction of virus-specific effector immune cell response limits virus replication and severe disease in mice infected with non-lethal West Nile virus Eg101 strain.
Kumar M, Roe K, O'Connell M, Nerurkar VR

Background: West Nile virus (WNV) is a neurotropic flavivirus that has emerged globally as a significant cause of viral encephalitis in humans. Herein, we investigated the immunological responses induced by two phylogenetically related WNV strains of lineage 1, WNV NY99, and WNV Eg101.
Methods: Eig…

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Seminars & Events
12 November 2015, 12:00 PM - 1:00 PM
Marc Horwitz, Ph.D.

How a Common Everyday Virus like Epstein-Barr Virus can Predispose for Multiple Sclerosis

22 October 2015, 10:00 AM
Colin Fitzpatrick, M.S.

Innovative Solutions for Quantitative Gene and Protein Expression - Visualize Whole Populations to the Single Cell- with Luminex, Flowcytometry, and Microscopy

20 October 2015, 2:00 PM
Bela Desai, Ph.D.

The Power of Multiplex Protein Analysis

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22 June 2015, 9:00 AM - 5:00 PM (Monday and Tuesday)

Software Carpentry Workshop

03 February 2015, 9:30 AM
Bela Desai, Ph.D.

Principles of Flow Cytometry and Applications

15 March 2013, 1:00 PM - 3:30 PM
Robert Bowers, Ph. D.

Using QIIME for Microbial Community Analysis

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Recent Grants
NIH/NIAID, R01AI119185 Defining a Protective Ebola Vaccine in Non-human Primates
08/28/2015 - 07/31/2019
Hawaii Community Foundation, 15ADVC-75878 West Nile Virus NS2B-NS3 Heterodimer as a Potential Target for Antiviral Drug Development
07/15/2015 - 01/14/2017
Department of Defense, U.S. Army Medical Research Acquisitions Administration, W81XWH-15-R-0015 US Army Medical Research Institute of Infectious Diseases (USAMRIID) Requirement to Develop, Produce and Deploy MAGPIX-Based Immunoassays
07/13/2015 - 07/12/2016
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