Publication Detail
Use of urea wash ELISA to distinguish Zika and dengue virus infections.
Tsai WY, Youn HH, Tyson J, Brites C, Tsai JJ, Pedroso C, Drexler JF, Balmaseda A, Harris E, Wang WK.
Citation
Tsai WY, Youn HH, Tyson J, Brites C, Tsai JJ, Pedroso C, Drexler JF, Balmaseda A, Harris E, Wang WK. (2018) Use of urea wash ELISA to distinguish Zika and dengue virus infections. Emerging Infectious Diseases 24(7):1355-1359.
Abstract
Serologic testing remains crucial for Zika virus diagnosis. We found that urea wash in a Zika virus nonstructural protein 1 IgG ELISA distinguishes secondary dengue virus infection from Zika virus infection with previous dengue (sensitivity 87.5%, specificity 93.8%). This test will aid serodiagnosis, serosurveillance, and monitoring of Zika complications in dengue-endemic regions.
| Link: | https://www.ncbi.nlm.nih.gov/pubmed/29912689 |
| PMID: | |
| PMCID: | PMC6038735 |