Publication Detail
Shift in epitope dominance of IgM and IgG responses to Plasmodium falciparum MSP1 block 4.
Chang SP, Kayatani AK, Terrientes ZI, Herrera S, Leke RG, Taylor DW.
Citation
Chang SP, Kayatani AK, Terrientes ZI, Herrera S, Leke RG, Taylor DW. (2010) Shift in epitope dominance of IgM and IgG responses to Plasmodium falciparum MSP1 block 4. Malaria Journal 9:14.
Abstract
Production of antibodies specific for each parental and recombinant MSP1 block 4 allele in different populations exposed to P. falciparum is consistent with balancing selection of the MSP1 block 4 region by the immune response of individuals in areas of both low and high malaria transmission. MSP1 block 4 determinants may be important in isolate-specific immunity to P. falciparum.
| Link: | http://www.ncbi.nlm.nih.gov/pubmed/20070906 |
| PMID: | 20070906 |
| PMCID: | PMC2837054 |