COBRE

Diane W. Taylor, Ph.D.

Professor
Department of Tropical Medicine, Medical Microbiology and Pharmacology
John A. Burns School of Medicine

Phone: 808-692-1608
Office: BSB 320J
Email: dwtaylor [at] hawaii.edu
Curriculum Vitae

Bio

Education


1968	B.A.	University of Hawaii at Manoa, Honolulu, HI
1970	M.S.	(Microbiology) University of Hawaii at Manoa, Honolulu, HI
1975	Ph.D.	(Zoology) University of Hawaii at Manoa, Honolulu, HI
1978	Post-Doctoral Fellow	(Tropical Medicine) University of Hawaii at Manoa, Honolulu, HI
1982	Staff Fellow	(Immunology) Laboratory of Microbial Immunity, NIAID, NIH, Bethesda, MD

Positions and Employment


1982-1986	Assistant Professor, Department of Biology, Georgetown University, Washington, DC
1986-1993	Associate Professor, Department of Biology, Georgetown University, Washington, DC
1993-2010	Professor, Department of Biology, Georgetown University, Washington, DC
2005-present	Professor, Department of Tropical Medicine, Medical Microbiology and Pharmacology, University of Hawaii at Manoa, Honolulu, HI

Other Experiences and Honors


1986-1997	Editorial Board, American Journal of Tropical Medicine and Hygiene
1986-1997	Reviewer, Infection and Immunity
1988-1991	Consultant for Beckton Dickinson
1989-1990	Consultant for Abbott Laboratories
1991	US patent Serial No. 939,113
1993-1997	Member, Tropical Medicine and Parasitology Study Section, NIAID, NIH
1997-1999	Consultant for Abbott Laboratories
2000	Dean’s Award for Excellence in Teaching, Georgetown University
2000	US representative of the African Immunological Societies
2001	Georgetown University Career Research Achievement Award

Research Keywords: Malaria, pregnancy, Cameroon

Selected Publications

Lloyd YM, Esemu LF, Antallan J, Thomas B, Tassi Yunga S, Obase B, Christine N, Leke RGF, Culleton R, Mfuh KO, Nerurkar VR, Taylor DW.
PCR-based detection of Plasmodium falciparum in saliva using mitochondrial cox3 and varATS primers.
Tropical Medicine and Health 2018 more details...
Tassi Yunga S, Fouda GG, Sama G, Ngu JB, Leke RGF, Taylor DW.
Increased susceptibility to Plasmodium falciparum in infants is associated with low, not high, placental malaria parasitemia.
Scientific Reports 2018 more details...
Abanda NN, Djieugoue JY, Khadka VS, Pefura-Yone EW, Mbacham WF, Vernet G, Penlap VM, Deng Y, Eyangoh SI, Taylor DW, Leke RGF.
Absence of hybridization with the wild-type and mutant rpoB probes in the Genotype MTBDRplus assay detects ‘disputed’ rifampicin mutations.
Clinical Microbiology and Infection 2017 more details...
Lloyd YM, Ngati EP, Salanti A, Leke RGF, Taylor DW.
A versatile, high through-put, bead-based phagocytosis assay for Plasmodium falciparum.
Scientific Reports 2017 more details...
Mfuh KO, Yunga ST, Esemu LF, Bekindaka ON, Yonga J, Djontu JC, Mbakop CD, Taylor DW, Nerurkar VR, Leke RGF.
Detection of Plasmodium falciparum DNA in saliva samples stored at room temperature: potential for a non-invasive saliva-based diagnostic test for malaria.
Malaria Journal 2017 more details...
Yunga ST, Kayatani AK, Fogako J, Leke RJI, Leke RGF, Taylor DW.
Timing of the human prenatal antibody response to Plasmodium falciparum antigens.
PLoS One 2017 more details...
Achonduh-Atijegbe OA, Mfuh KO, Mbange AH, Chedjou JP, Taylor DW, Nerurkar VR, Mbacham WF, Leke R.
Prevalence of malaria, typhoid, toxoplasmosis and rubella among febrile children in Cameroon.
BMC Infectious Diseases 2016 more details...
Babakhanyan A, Ekali GL, Dent A, Kazura J, Nguasong JT, Fodjo BAY, Yuosembom EK, Esemu LF, Taylor DW, Leke RGF.
Maternal human immunodeficiency virus-associated hypergammaglobulinemia reduces transplacental transfer of immunoglobulin G to Plasmodium falciparum antigens in Cameroonian neonates.
Open Forum Infectious Diseases 2016 more details...
Babakhanyan A, Leke RG, Salanti A, Bobbili N, Gwanmesia P, Leke RJ, Quakyi IA, Chen JJ, Taylor DW.
The antibody response of pregnant Cameroonian women to VAR2CSA ID1-ID2a, a small recombinant protein containing the CSA-binding site.
PLoS One 2014 more details...
Tutterrow YL, Avril M, Singh K, Long CA, Leke RJ, Sama G, Salanti A, Smith JD, Leke RG, Taylor DW.
High levels of antibodies to multiple domains and strains of VAR2CSA correlate with the absence of placental malaria in Cameroonian women living in an area of high Plasmodium falciparum transmission.
Infection and Immununity 2012 more details...
Tutterrow YL, Salanti A, Avril M, Smith JD, Pagano IS, Ako S, Fogako J, Leke RG, Taylor DW.
High avidity antibodies to full-length VAR2CSA correlate with absence of placental malaria.
PLoS One 2012 more details...
Leke RG, Taylor DW.
The use of intermittent preventive treatment with sulfadoxine-pyrimethamine for preventing malaria in pregnant women.
Clinical Infectious Diseases 2011 more details...
Sander AF, Salanti A, Lavstsen T, Nielsen MA, Theander TG, Leke RG, Lo YY, Bobbili N, Arnot DE, Taylor DW.
Positive selection of Plasmodium falciparum parasites with multiple var2csa-type PfEMP1 genes during the course of infection in pregnant women.
Journal of Infectious Diseases 2011 more details...
Silver KL, Conroy AL, Leke RG, Leke RJ, Gwanmesia P, Molyneux ME, Taylor DW, Wallace DT, Rogerson SJ, Kain KC.
Circulating soluble endoglin levels in pregnant women in Cameroon and Malawi–associations with placental malaria and fetal growth restriction.
PLoS One 2011 more details...
Chang SP, Kayatani AK, Terrientes ZI, Herrera S, Leke RG, Taylor DW.
Shift in epitope dominance of IgM and IgG responses to Plasmodium falciparum MSP1 block 4.
Malaria Journal 2010 more details...
Leke RF, Bioga JD, Zhou J, Fouda GG, Leke RJ, Tchinda V, Megnekou R, Fogako J, Sama G, Gwanmesia P, Bomback G, Nama C, Diouf A, Bobbili N, Taylor DW.
Longitudinal studies of Plasmodium falciparum malaria in pregnant women living in a rural Cameroonian village with high perennial transmission.
American Journal of Tropical Medicine and Hygiene 2010 more details...
Silver KL, Zhong K, Leke RG, Taylor DW, Kain KC.
Dysregulation of angiopoietins is associated with placental malaria and low birth weight.
PLoS One 2010 more details...
Thevenon AD, Zhou JA, Megnekou R, Ako S, Leke RG, Taylor DW.
Elevated levels of soluble TNF receptors 1 and 2 correlate with Plasmodium falciparum parasitemia in pregnant women: potential markers for malaria-associated inflammation.
Journal of Immunology 2010 more details...
Pong CK, Thevenon AD, Zhou JA, Taylor DW.
Influence of human chorionic gonadotropin (hCG) on in vitro growth of Plasmodium falciparum.
Malaria Journal 2009 more details...
Thevenon AD, Leke RG, Suguitan AL, Zhou JA, Taylor DW.
Genetic polymorphisms of mannose-binding lectin do not influence placental malaria but are associated with preterm deliveries.
Infection and Immunity 2009 more details...
Wanji S, Tendongfor N, Nji T, Esum M, Che JN, Nkwescheu A, Alassa F, Kamnang G, Enyong PA, Taylor MJ, Hoerauf A, Taylor DW.
Community-directed delivery of doxycycline for the treatment of onchocerciasis in areas of co-endemicity with loiasis in Cameroon.
Parasite Vectors 2009 more details...

Grants

Grant No / Title: R21AI109449 / Immunity to Placental Malaria: Persistence of Antibodies to VAR2CSA
Status / Agency: Awarded / NIH/NIAID
Start Date / End Date: 19 December 2014 / 30 November 2016
Grant No / Title: R21AI105286 / Defining Immunity to Placental Malaria using a Multi-assay Predictive Model
Status / Agency: Awarded / NIH/NIAID
Start Date / End Date: 01 March 2014 / 28 February 2016
Grant No / Title: T37MD008636 / International Biomedical Research Training for Hawaiian & Pacific Island Students
Status / Agency: Awarded / NIH/NIMHD
Start Date / End Date: 01 December 2013 / 30 November 2018
Grant No / Title: D43TW009074 / Training of Cameroonian Scientists in Research on Malaria
Status / Agency: Awarded / NIH/FIC
Start Date / End Date: 01 August 2011 / 30 July 2016