Evaluation of a new commercially available immunoglobulin M capture enzyme-linked immunosorbent assay for diagnosis of dengue infection.

Namekar M, Ellis EM, O’Connell M, Elm J, Gurary A, Park SY, Imrie A, Nerurkar VR.

Citation

Namekar M, Ellis EM, O’Connell M, Elm J, Gurary A, Park SY, Imrie A, Nerurkar VR. (2013) Evaluation of a new commercially available immunoglobulin M capture enzyme-linked immunosorbent assay for diagnosis of dengue infection. Journal of Clinical Microbiology

Abstract

We evaluated the FDA cleared InBios Dengue virus (DENV) IgM Capture ELISA for qualitative detection of anti-DENV IgM antibodies from 79 serum samples obtained from dengue-infected patients or suspected cases. Agreement, sensitivity and specificity of InBios assay compared to ‘gold standard’ in-house DENV IgM Capture ELISA was 94, 92 and 94%, respectively. We conclude that InBios DENV IgM Capture ELISA can be effectively used for rapid diagnosis of acute or recent DENV infection.