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In vitro effects of selenium deficiency on West Nile virus replication and cytopathogenicity.

Verma S, Molina Y, Lo YY, Cropp B, Nakano C, Yanagihara R, Nerurkar VR.

Citation

Verma S, Molina Y, Lo YY, Cropp B, Nakano C, Yanagihara R, Nerurkar VR. (2008) In vitro effects of selenium deficiency on West Nile virus replication and cytopathogenicity. Virology Journal 5:66.


Abstract

Overall results demonstrate that the in vitro Se-deficient model can be used to study responses of WNV to this essential nutrient. Although Se deficiency has no in vitro effect on WNV replication kinetics, adequate Se is presumably critical to protect WNV-infected cells against virus-induced cell death.


Link: http://www.ncbi.nlm.nih.gov/pubmed/18513435
PMID: 18513435
PMCID: PMC2453119