Diane E. Griffin, M.D., Ph.D.
University Distinguished Service Professor W. Harry Feinstone Department of Molecular Microbiology and Immunology Johns Hopkins Bloomberg School of Public Health Baltimore, Maryland
Phone: (410) 955-3459
Office:
Email: dgriffin [at] jhsph.edu
Curriculum Vitae
Selected Publications
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Fiebelkorn AP, Coleman LA, Belongia EA, Freeman SK, York D, Bi D, Kulkarni A, Audet S, Mercader S, McGrew M, Hickman CJ, Bellini WJ, Shivakoti R, Griffin DE, Beeler J.
Measles virus neutralizing antibody response, cell-mediated immunity, and immunoglobulin G antibody avidity before and after receipt of a third dose of measles, mumps, and rubella vaccine in young adults.
Journal of Infectious Diseases
2016
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Ludlow M, Kortekaas J, Herden C, Hoffmann B, Tappe D, Trebst C, Griffin DE, Brindle HE, Solomon T, Brown AS, van Riel D, Wolthers KC, Pajkrt D, Wohlsein P, Martina BE, Baumgartner W, Verjans GM, Osterhaus AD.
Neurotropic virus infections as the cause of immediate and delayed neuropathology.
Acta Neuropathologica
2016
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Kulcsar KA, Baxter VK, Abraham R, Nelson A, Griffin DE.
Distinct immune responses in resistant and susceptible strains of mice during neurovirulent alphavirus encephalomyelitis.
Journal of Virology
2015
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Potter MC, Baxter VK, Mathey RW, Alt J, Rojas C, Griffin DE, Slusher BS.
Neurological sequelae induced by alphavirus infection of the CNS are attenuated by treatment with the glutamine antagonist 6-diazo-5-oxo-l-norleucine.
Journal of Neurovirology
2015
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Schultz KL, Vernon PS, Griffin DE.
Differentiation of neurons restricts arbovirus replication and increases expression of the alpha isoform of IRF-7.
Journal of Virology
2015
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Shivakoti R, Hauer D, Adams RJ, Lin WH, Duprex WP, de Swart RL, Griffin DE.
Limited in vivo production of type I or type III interferon after infection of macaques with vaccine or wild-type strains of measles virus.
Journal of Interferon and Cytokine Research
2015
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Bogerd HP, Skalsky RL, Kennedy EM, Furuse Y, Whisnant AW, Flores O, Schultz KL, Putnam N, Barrows NJ, Sherry B, Scholle F, Garcia-Blanco MA, Griffin DE, Cullen BR.
Replication of many human viruses is refractory to inhibition by endogenous cellular microRNAs.
Journal of Virology
2014
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Chiu YL, Shan L, Huang H, Haupt C, Bessell C, Canaday DH, Zhang H, Ho YC, Powell JD, Oelke M, Margolick JB, Blankson JN, Griffin DE, Schneck JP.
Sprouty-2 regulates HIV-specific T cell polyfunctionality.
Journal of Clinical Investigation
2014
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Griffin DE.
Measles virus and the nervous system.
Handbook of Clinical Neurology
2014
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Kulcsar KA, Baxter VK, Greene IP, Griffin DE.
Interleukin 10 modulation of pathogenic Th17 cells during fatal alphavirus encephalomyelitis.
Proceedings of the National Academy of Sciences U S A
2014
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Lin WH, Pan CH, Adams RJ, Laube BL, Griffin DE.
Vaccine-induced measles virus-specific T cells do not prevent infection or disease but facilitate subsequent clearance of viral RNA.
MBio
2014
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Lee EY, Schultz KL, Griffin DE.
Mice deficient in interferon-gamma or interferon-gamma receptor 1 have distinct inflammatory responses to acute viral encephalomyelitis.
PLoS One
2013
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Lin WH, Vilalta A, Adams RJ, Rolland A, Sullivan SM, Griffin DE.
Vaxfectin adjuvant improves antibody responses of juvenile rhesus macaques to a DNA vaccine encoding the measles virus hemagglutinin and fusion proteins.
Journal of Virology
2013
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Metcalf TU, Baxter VK, Nilaratanakul V, Griffin DE.
Recruitment and retention of B cells in the central nervous system in response to alphavirus encephalomyelitis.
Journal of Virology
2013
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Polack FP, Lydy SL, Lee SH, Rota PA, Bellini WJ, Adams RJ, Robinson HL, Griffin DE.
Poor immune responses of newborn rhesus macaques to measles virus DNA vaccines expressing the hemagglutinin and fusion glycoproteins.
Clinical and Vaccine Immunology
2013
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Shivakoti R, Siwek M, Hauer D, Schultz KL, Griffin DE.
Induction of dendritic cell production of type I and type III interferons by wild-type and vaccine strains of measles virus: role of defective interfering RNAs.
Journal of Virology
2013
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Snyder JE, Kulcsar KA, Schultz KL, Riley CP, Neary JT, Marr S, Jose J, Griffin DE, Kuhn RJ.
Functional characterization of the alphavirus TF protein.
Journal of Virology
2013
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Griffin DE, Lin WH, Pan CH.
Measles virus, immune control and persistence.
FEMS Microbiology Review
2012
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Lin WH, Kouyos RD, Adams RJ, Grenfell BT, Griffin DE.
Prolonged persistence of measles virus RNA is characteristic of primary infection dynamics.
Proceedings of the National Academy of Sciences U S A
2012
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Moss WJ, Griffin DE.
Measles.
Lancet
2012
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Okamoto Y, Vricella LA, Moss WJ, Griffin DE.
Immature CD4+CD8+ thymocytes are preferentially infected by measles virus in human thymic organ cultures.
PLoS One
2012
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von Messling VA, Griffin DE.
How respiratory viruses overcome mucosal defenses and exploit the unique environment of the respiratory tract.
Current Opinions in Virology
2012
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Griffin DE, Metcalf T.
Clearance of virus infection from the CNS.
Current Opinions in Virology
2011
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Griffin DE.
Viral encephalomyelitis.
PLoS Pathogens
2011
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Lin WH, Griffin DE, Rota PA, Papania M, Cape SP, Bennett D, Quinn B, Sievers RE, Shermer C, Powell K, Adams RJ, Godin S, Winston S.
Successful respiratory immunization with dry powder live-attenuated measles virus vaccine in rhesus macaques.
Proceedings of the National Academy of Sciences USA
2011
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Metcalf TU, Griffin DE.
Alphavirus-induced encephalomyelitis: antibody-secreting cells and viral clearance from the nervous system.
Journal of Virology
2011
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Moss WJ, Griffin DE.
Measles.
Lancet
2011
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Bergen MJ, Pan CH, Greer CE, Legg HS, Polo JM, Griffin DE.
Comparison of the immune responses induced by chimeric alphavirus-vectored and formalin-inactivated alum-precipitated measles vaccines in mice.
PLoS One
2010
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Griffin DE.
Measles virus-induced suppression of immune responses.
Immunology Review
2010
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Griffin DE.
Recovery from viral encephalomyelitis: immune-mediated noncytolytic virus clearance from neurons.
Immunological Research
2010
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Griffin DE.
Emergence and re-emergence of viral diseases of the central nervous system.
Progress in Neurobiology
2010
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Ndhlovu ZM, Oelke M, Schneck JP, Griffin DE.
Dynamic regulation of functionally distinct virus-specific T cells.
Proceedings of the National Academy of Sciences USA
2010
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Pan CH, Greer CE, Hauer D, Legg HS, Lee EY, Bergen MJ, Lau B, Adams RJ, Polo JM, Griffin DE.
A chimeric alphavirus replicon particle vaccine expressing the hemagglutinin and fusion proteins protects juvenile and infant rhesus macaques from measles.
Journal of Virology
2010
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