Publication Detail
Characterization of the ectodomain of the envelope protein of dengue virus type 4: expression, membrane association, secretion and particle formation in the absence of precursor membrane protein.
Hsieh SC, Tsai WY, Nerurkar VR, Wang WK.
Citation
Hsieh SC, Tsai WY, Nerurkar VR, Wang WK. (2014) Characterization of the ectodomain of the envelope protein of dengue virus type 4: expression, membrane association, secretion and particle formation in the absence of precursor membrane protein. PLoS One 9(6):e100641.
Abstract
Considering the enhancement of DENV infectivity by anti-prM antibodies, our findings provide new insights into the expression and secretion of E protein ectodomain in the absence of prM protein and contribute to future subunit vaccine design.
| Link: | http://www.ncbi.nlm.nih.gov/pubmed/24950216 |
| PMID: | 24950216 |
| PMCID: | PMC4065094 |