Single-Injection Vaccines

Date/Time: 11 December 2017, 12:00 PM
Speaker: Ana Jaklenec, Ph.D.
Speaker Affiliation: Research Scientist, David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Maryland
Venue: John A. Burns School of Medicine, Medical Education Building Auditorium (Room 315)

For more info: Cori Watanabe 808 692-1654
Description: Vaccination is the most effective method for preventing infectious diseases, yet each year millions of infants and children, mainly in the developing world, remain unprotected due to logistical challenges of obtaining the required series of injections. Single-injection vaccines have the potential to mitigate these issues, but present many technical challenges related to release kinetics and vaccine stability. We address these with a novel, polymer-based, injectable drug-delivery platform with pulsatile release over several months post administration. This technology allows for control of release kinetics independent of the encapsulated drug, enabling easier formulation of complex and labile molecules, such as vaccines.
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