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News & Research Highlights
07 December 2018: Efficacy of A Recombinant Subunit Protein-Based Zika Virus Vaccine in Non-human Primates
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Dr. Axel T. Lehrer, a former COBRE Small Grants Program awardee, and his research team have successfully developed a recombinant subunit protein-based vaccine for Zika virus. Previously, he demonstrated that this vaccine was effective in protecting mice from Zika virus challenge. These studies have …


09 November 2018: Stopping the Sting
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The 20-year pursuit of developing effective treatment regimens for box jellyfish envenomation by Angel Yanagihara, a Fulbright Specialist and former COBRE Small Grants Program awardee, is featured in the November 9, 2018 issue of Science.
https://www.sciencemag.org/news/2018/11/jellyfish-almost-kil...


08 October 2018: Efficacy of A Recombinant Subunit Protein-Based Zika Virus Vaccine

Zika Virus (ZIKV), a virus with no severe clinical symptoms or sequelae previously associated with human infection, became a public health threat following an epidemic in French Polynesia in 2013-2014 that resulted in neurological complications associated with infection. Although no treatment curren…


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Recent Publications
Frontiers in Microbiology, 2019, Deletion of pregnancy zone protein and murinoglobulin-1 restricts the pathogenesis of West Nile virus infection in mice.
Krause K, Azouz F, Nakano E, Nerurkar VR, Kumar M.

West Nile virus (WNV) is an enveloped positive-stranded RNA virus that causes meningitis, encephalitis, and acute flaccid paralysis in humans. There are no therapeutic agents available for use against WNV infection. Alpha-2 macroglobulin (A2M) is a major plasma proteinase inhibitor that also has imp…


Viruses, 2019, Molecular phylogeny of mobatviruses (Hantaviridae) in Myanmar and Vietnam.
Arai S, Kikuchi F, Bawm S, Son NT, Lin KS, Tu VT, Aoki K, Tsuchiya K, Tanaka-Taya K, Morikawa S, Oishi K, Yanagihara R.

The discovery of highly divergent lineages of hantaviruses (family Hantaviridae) in shrews, moles, and bats of multiple species raises the possibility that non-rodent hosts may have played a significant role in their evolutionary history. To further investigate this prospect, total RNA was extracted…


BMC Genomics, 2018, Plasma small ncRNA pair panels as novel biomarkers for early-stage lung adenocarcinoma screening.
Dou Y, Zhu Y, Ai J, Chen H, Liu H, Borgia JA, Li X, Yang F, Jiang B, Wang J, Deng Y.

BACKGROUND:
Lung cancer is a major cause of cancer-related mortality worldwide, and around two-thirds of patients have metastasis at diagnosis. Thus, detecting lung cancer at an early stage could reduce mortality. Aberrant levels of circulating small non-coding RNAs (small ncRNAs) are potential dia…


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Seminars & Events
19 July 2019, 11:00 AM - 12:00 PM
Weida Tong, Ph.D.
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Artificial Intelligence and Machine Learning – The perspective from a FDA project


09 July 2019, 10:30 AM
Urvinder Kaur S, M.Sc.

Study of Gut Microbiota in Perinatally HIVInfected Children and its Potential Role in Inflammation and Host Metabolism


07 May 2019, 2:30 PM
Nelson L. Michael, M.D., Ph.D.
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Vaccines for Infectious Diseases at the Walter Reed Army Institute of Research: AIDS to Zika


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Workshops
06 June 2019, 10:00 AM
Lisa Bellemare

FLOW CYTOMETRY AND CELL SORTING FOR EVERY TYPE OF BIOLOGICAL SAMPLES


15 February 2019, 9:00 AM - 12:00 PM
Drs. Youping Deng, Mark Menor & Vedbar Khadka

Genome Assembly, Evaluation and Visualization


17 October 2018, 11:00 AM
Bela Desai, Ph.D.

Improving Protein Detection: Accurate, High-Sensitivity and High-Throughput Analysis of Biomarkers


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Recent Grants
NIH/FIC, 1D71TW010434-01A1 Sustainable Research Training and Capacity Building in Liberia for Emerging Viral Epidemics
09/08/2017 - 08/31/2019
NIH/OD, R21OD024896 A Guinea Pig Model of Zika Virus Disease
09/01/2017 - 08/31/2019
NIH/FIC, 2D43TW009345-06 Northern/Pacific Universities Global Health Research Training Consortium
07/01/2017 - 06/30/2022
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