Home UH Manoa

News & Research Highlights
20 August 2019: Military Health System Research Symposium

Former COBRE Small Grants Program awardee, Angel Yanagihara, attended the Military Health System Research Symposium, held in Kissimmee, Florida, on August 19-21 2019, where she presented findings from a collaborative project, entitled “Lethal Box Jellyfish Envenomation Syndromes”, conducted with Cat…

07 December 2018: Efficacy of A Recombinant Subunit Protein-Based Zika Virus Vaccine in Non-human Primates

Dr. Axel T. Lehrer, a former COBRE Small Grants Program awardee, and his research team have successfully developed a recombinant subunit protein-based vaccine for Zika virus. Previously, he demonstrated that this vaccine was effective in protecting mice from Zika virus challenge. These studies have …

09 November 2018: Stopping the Sting

The 20-year pursuit of developing effective treatment regimens for box jellyfish envenomation by Angel Yanagihara, a Fulbright Specialist and former COBRE Small Grants Program awardee, is featured in the November 9, 2018 issue of Science.

View more ...

Recent Publications
PLoS Neglected Tropical Diseases, 2019, Serological evidence of Ebola virus exposure in dogs from affected communities in Liberia: a preliminary report.
Haun BK, Kamara V, Dweh AS, Garalde-Machida K, Forkay SSE, Takaaze M, Namekar M, Wong TAS, Bell-Gam Woto AER, Humphreys P, Weeks OI, Fallah MP, Berestecky JM, Nerurkar VR, Lehrer AT.

Filoviruses such as Ebola virus (EBOV) cause outbreaks of viral hemorrhagic fevers for which no FDA-approved vaccines or drugs are available. The 2014-2016 EBOV outbreak in West Africa infected approximately 30,000 people, killing more than 11,000 and affecting thousands more in areas still sufferin…

Viruses, 2019, Complex history of codiversification and host switching of a newfound soricid-borne orthohantavirus in North America.
Liphardt SW, Kang HJ, Dizney LJ, Ruedas LA, Cook JA, Yanagihara R.

Orthohantaviruses are tightly linked to the ecology and evolutionary history of their mammalian hosts. We hypothesized that in regions with dramatic climate shifts throughout the Quaternary, orthohantavirus diversity and evolution are shaped by dynamic host responses to environmental change through …

Scientific Reports, 2019, Dakrong virus, a novel mobatvirus (Hantaviridae) harbored by the Stoliczka's Asian trident bat (Aselliscus stoliczkanus) in Vietnam.
Arai S, Aoki K, Nguyen ST, Vuong TV, Kikuchi F, Kinoshita G, Fukui D, Hoang TT, Gu SH, Yoshikawa Y, Tanaka-Taya K, Morikawa S, Yanagihara R, Oishi K.

The recent discovery of genetically distinct shrew- and mole-borne viruses belonging to the newly defined family Hantaviridae (order Bunyavirales) has spurred an extended search for hantaviruses in RNAlater-preserved lung tissues from 215 bats (order Chiroptera) representing five families (Hipposide…

View more ...
Seminars & Events
11 September 2019, 12:00 PM - 1:00 PM
Gregg M. Nakano, M.A.L.D.

Global Health Security in the Pacific Century

28 August 2019, 12:00 PM - 1:00 PM
Edward P. Desmond, Ph.D., D (ABMM)

DNA Sequencing to Determine TB Drug Susceptibility

28 August 2019, 9:00AM
1) Esther Ellis, Ph.D. 2) Brett Ellis, Ph.D.

US Virgin Islands Public Health Infectious Disease and Hurricane Recovery

View more ...

06 June 2019, 10:00 AM
Lisa Bellemare


15 February 2019, 9:00 AM - 12:00 PM
Drs. Youping Deng, Mark Menor & Vedbar Khadka

Genome Assembly, Evaluation and Visualization

17 October 2018, 11:00 AM
Bela Desai, Ph.D.

Improving Protein Detection: Accurate, High-Sensitivity and High-Throughput Analysis of Biomarkers

View more ...

Recent Grants
NIH/FIC, 1D71TW010434-01A1 Sustainable Research Training and Capacity Building in Liberia for Emerging Viral Epidemics
09/08/2017 - 08/31/2019
NIH/OD, R21OD024896 A Guinea Pig Model of Zika Virus Disease
09/01/2017 - 08/31/2019
NIH/FIC, 2D43TW009345-06 Northern/Pacific Universities Global Health Research Training Consortium
07/01/2017 - 06/30/2022
View more ...