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News & Research Highlights
24 October 2016: New NIH Grant

COBRE Investigator, Mukesh Kumar, DVM, MS, PhD, has received a major grant to support his work to discover an effective treatment for Flavivirus infections, the leading cause of epidemic encephalitis (inflammation of the brain) worldwide.


07 September 2016: Awardees of the 2016 COBRE Small Grants Program

Pilot funding has been awarded to two highly meritorious proposals, submitted in response to the COBRE Small Grants Program funding opportunity announcement (FOA).

Mukesh Kumar, Ph.D.
Guinea Pig Model of In Utero Zika Virus Infection

Saguna Verma, Ph.D.
RNA-seq Analysis of Persisten…

23 August 2016: Leveraging of Small Grants Program Funding

Support from the COBRE Small Grants Program to two investigators has been successfully leveraged into NIH awards.

1R21NS099838-01 (Mukesh Kumar, Ph.D.)
Defining the Function of Schlafen4 in the Pathogenesis of Flavivirus Encephalitis
Members of the Flavivirus genus are leading causes of epi…

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Recent Publications
Infection Genetics and Evolution, 2016, Molecular phylogeny of a genetically divergent hantavirus harbored by the Geoffroy's rousette (Rousettus amplexicaudatus), a frugivorous bat species in the Philippines.
Arai S, Taniguchi S, Aoki K, Yoshikawa Y, Kyuwa S, Tanaka-Taya K, Masangkay JS, Omatsu T, Puentespina R, Watanabe S, Alviola P, Alvarez J, Eres E, Cosico E, Quibod MN, Morikawa S, Yanagihara R, Oishi K.

The recent discovery of genetically distinct hantaviruses in multiple species of shrews and moles (order Eulipotyphla, families Soricidae and Talpidae) prompted a further exploration of their host diversification and geographic distribution by analyzing lung tissues from 376 fruit bats representing …

Tropical Medicine and Health, 2016, Dahonggou Creek virus, a divergent lineage of hantavirus harbored by the long-tailed mole (Scaptonyx fusicaudus).
Kang HJ, Gu SH, Cook JA, Yanagihara R.

Novel hantaviruses, recently detected in moles (order Eulipotyphla, family Talpidae) from Europe, Asia, and North America would predict a broader host range and wider ecological diversity. Employing RT-PCR, archival frozen tissues from the Chinese shrew mole (Uropsilus soricipes), broad-footed mole …

Toxins (Basel), 2016, Experimental assays to assess the efficacy of vinegar and other topical first-aid approaches on cubozoan (Alatina alata) tentacle firing and venom toxicity.
Yanagihara AA, Wilcox C, King R, Hurwitz K, Castelfranco AM.

Despite the medical urgency presented by cubozoan envenomations, ineffective and contradictory first-aid management recommendations persist. A critical barrier to progress has been the lack of readily available and reproducible envenomation assays that (1) recapitulate live-tentacle stings; (2) allo…

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Seminars & Events
26 October 2016, 12:00 PM - 1:00 PM
Wayne Melrose, Ph.D.

Worms are More Dangerous than We Think: Immuno-modulation of the Host Immune Response by Nematode Parasites

20 October 2016, 10:00 AM - 11:30 AM
Michele Langner & Jason Smith

Production Power Sequencing on the Benchtop: Meet the Illumina NextSeq

19 October 2016, 12:00 PM - 1:00 PM
Youping Deng, Ph.D.

Development of Precision Medicine through Integrative DNA- and RNA-seq Data Analysis

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21 October 2016, 10:00 AM
Alexandra Gurary, Ph.D.

Attune Nxt Training

20 October 2016, 03:30 PM
Alexandra Gurary, Ph.D.

Luminex Acquisition Software Training

20 October 2016, 10:00 AM
Alexandra Gurary, Ph.D.

Attune Nxt Training

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Recent Grants
NIH/NINDS, R21NS099838 Defining the Function of Schlafen4 in the Pathogenesis of Flavivirus Encephalitis
09/01/2016 - 08/31/2018
NIH/NIEHS, R21ES027230 Pathogenesis of Life Threatening Box Jellyfish Envenomation and Irukandji Syndrome
09/01/2016 - 08/31/2018
NIH/NIAID, R01AI119185 Defining a Protective Ebola Vaccine in Non-human Primates
08/28/2015 - 07/31/2019
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