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News & Research Highlights
07 December 2018: Efficacy of A Recombinant Subunit Protein-Based Zika Virus Vaccine in Non-human Primates

Dr. Axel T. Lehrer, a former COBRE Small Grants Program awardee, and his research team have successfully developed a recombinant subunit protein-based vaccine for Zika virus. Previously, he demonstrated that this vaccine was effective in protecting mice from Zika virus challenge. These studies have …

09 November 2018: Stopping the Sting

The 20-year pursuit of developing effective treatment regimens for box jellyfish envenomation by Angel Yanagihara, a Fulbright Specialist and former COBRE Small Grants Program awardee, is featured in the November 9, 2018 issue of Science.

08 October 2018: Efficacy of A Recombinant Subunit Protein-Based Zika Virus Vaccine

Zika Virus (ZIKV), a virus with no severe clinical symptoms or sequelae previously associated with human infection, became a public health threat following an epidemic in French Polynesia in 2013-2014 that resulted in neurological complications associated with infection. Although no treatment curren…

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Recent Publications
BMC Genomics, 2018, Plasma small ncRNA pair panels as novel biomarkers for early-stage lung adenocarcinoma screening.
Dou Y, Zhu Y, Ai J, Chen H, Liu H, Borgia JA, Li X, Yang F, Jiang B, Wang J, Deng Y.

Lung cancer is a major cause of cancer-related mortality worldwide, and around two-thirds of patients have metastasis at diagnosis. Thus, detecting lung cancer at an early stage could reduce mortality. Aberrant levels of circulating small non-coding RNAs (small ncRNAs) are potential dia…

BMC Systems Biology, 2018, The emerging role of microRNA-4487/6845-3p in Alzheimer's disease pathologies is induced by Abeta25-35 triggered in SH-SY5Y cell.
Hu L, Zhang R, Yuan Q, Gao Y, Yang MQ, Zhang C, Huang J, Sun Y, Yang W, Yang JY, Min ZL, Cheng J, Deng Y, Hu X.

Accumulation of amyloid beta-peptide (Abeta) is implicated in the pathogenesis and development of Alzheimer’s disease (AD). Neuron-enriched miRNA was aberrantly regulated and may be associated with the pathogenesis of AD. However, regarding whether miRNA is involved in the accumulation …

BMC Systems Biology , 2018, Increased AURKA promotes cell proliferation and predicts poor prognosis in bladder cancer.
Guo M, Lu S, Huang H, Wang Y, Yang MQ, Yang Y, Fan Z, Jiang B, Deng Y.

Bladder cancer (BC) is the most common cancer of the urinary bladder and upper tract, in which the clinical management is limited. AURKA (aurora kinase A) has been identified as an oncogene in cancer development; however, its potential role and underlying mechanisms in the progression o…

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Seminars & Events
07 May 2019, 2:30 PM
Nelson L. Michael, M.D., Ph.D.

Vaccines for Infectious Diseases at the Walter Reed Army Institute of Research: AIDS to Zika

08 April 2019, 12:00 PM
Carlos Brites, M.D., Ph.D.

Endemic and Epidemic Infectious Diseases in Brazil / 1: HIV-1 and HTLV-1 co-infection and impact on survival / 2: Overview of epidemic Zika virus infection in Bahia

20 March 2019, 9:00 AM - 11:30 AM
Diane E. Griffin, M.D., Ph.D. (1), David A. Relman, M.D. (2), Edward G. Ruby, Ph.D. (3), Eric Rasmussen, M.D. (4)


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06 June 2019, 10:00 AM
Lisa Bellemare


15 February 2019, 9:00 AM - 12:00 PM
Drs. Youping Deng, Mark Menor & Vedbar Khadka

Genome Assembly, Evaluation and Visualization

17 October 2018, 11:00 AM
Bela Desai, Ph.D.

Improving Protein Detection: Accurate, High-Sensitivity and High-Throughput Analysis of Biomarkers

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Recent Grants
NIH/FIC, 1D71TW010434-01A1 Sustainable Research Training and Capacity Building in Liberia for Emerging Viral Epidemics
09/08/2017 - 08/31/2019
NIH/OD, R21OD024896 A Guinea Pig Model of Zika Virus Disease
09/01/2017 - 08/31/2019
NIH/FIC, 2D43TW009345-06 Northern/Pacific Universities Global Health Research Training Consortium
07/01/2017 - 06/30/2022
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