One of the most highly divergent lineages of hantaviruses is represented by Nova virus (NVAV), originally detected in archival liver tissue from a single European mole (Talpa europaea), captured in Zala County, Hungary, in July 1999. As evidenced by RT-PCR and confirmed by DNA sequencing, a high pre…

The complete genome of a newfound hantavirus, designated Bowe virus, was amplified and sequenced from ethanol-fixed intercostal muscle of a Doucet’s musk shrew (Crocidura douceti) (order Soricomorpha), captured in southwestern Guinea. Although not ideal and far inferior to frozen tissues or tissues …

A new study of well-characterized serum samples collected from dengue patients in Hawaii, Vietnam, Niue, Singapore and American Samoa has shown that the InBios DENV Detect IgM Capture ELISA outperformed an in-house DENV IgM antibody capture (MAC) ELISA, as judged by sensitivity and specificity of 92…

The P. falciparum Merozoite Surface Protein 1-42 (MSP1-42) is one of the most studied malaria subunit vaccine candidates. The N-terminal fragment of MSP1-42, MSP1-33, is primarily composed of allelic sequences, and has been shown to possess T helper epitopes that influence protective antibody respon…

Background: Hokkaido hantavirus (HOKV) was identified originally in the grey red-backed vole (Myodes rufocanus) in Hokkaido, Japan. Subsequent studies showed different genetic lineages of HOKV in Sakhalin, Buryatia and Far Eastern regions of Russia and in China.
Methods: Tissues from 68 arvicolid r…

Dengue virus (DENV) is the leading cause of arboviral diseases in humans worldwide. The envelope (E) protein of DENV is the major target of neutralizing antibodies (Abs). Previous studies have shown that a significant proportion of anti-E Abs in human serum after DENV infection recognize the highly …