Animal models are critical to understand the transmission and pathogenesis of infectious diseases and to develop countermeasures for their prevention and spread. Here, we report that immunocompetent Dunkin Hartley guinea pigs are susceptible to infection by a contemporary American strain of Zika vir…

The purpose of the Centers of Biomedical Research Excellence (COBRE) Small Grants Program is to provide support via three funding mechanisms to University of Hawaii (UH) faculty engaged in research in tropical medicine, medical microbiology, immunology, and/or emerging infectious diseases. However, …

An instrument-dedicated, BSL-2+-certified, aerosol-management system has been installed to isolate the BD FACSAria IIu Flow Cytometer from other instrumentation within the Molecular and Cellular Immunology Core. This customized bioBUBBLE enclosure, which is retrofitted with a dedicated ventilation s…

Stings from the hydrozoan species in the genus Physalia cause intense, immediate skin pain
and elicit serious systemic effects. There has been much scientific debate about the most appropriate first aid for these stings, particularly with regard to whether vinegar use is appropriate (most current r…

Major gaps remain in our understanding of the ecology, evolution, biodiversity, biogeography, extinction risk, and adaptive potential of reef building corals. One of the central challenges remains that there are few informative genetic markers for studying boundaries between species, and variation w…

Background: Animal models are critical to understand disease and to develop countermeasures for the ongoing epidemic of Zika virus (ZIKV). Here we report that immunocompetent guinea pigs are susceptible to infection by a contemporary American strain of ZIKV.
Methods: Dunkin-Hartley guinea pigs were…