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News & Research Highlights
14 April 2014: New Insights into the Molecular Phylogeny of Muju Virus
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The genome of Muju virus (MUJV), identified originally in the royal vole (Myodes regulus) in Korea, was fully sequenced to ascertain its genetic and phylogenetic relationship with Puumala virus (PUUV), harbored by the bank vole (My. glareolus), and a PUUV-like virus, named Hokkaido virus (HOKV), in …


24 January 2014: Discovery of Aminoglycoside-susceptible Burkholderia pseudomallei

Gentamicin has been used as a major ingredient of Ashdown’s agar, a selective medium for Burkholderia pseudomallei, the causative agent of melioidosis. Recently we found that clinical B. pseudomallei strains from Salavak, Malaysian Borneo, were sensitive to gentamicin, and could not be selected by A…


20 January 2014: Rediscovery and New Beginnings
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The history of hantaviruses has been marked by rediscovery and new beginnings. In an invited review, the host range, genetic diversity and geographic distribution of hantaviruses harbored by non-rodent small mammals are summarized to gain insights into their evolutionary origins and phylogeography. …


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Recent Publications
Viruses, 2014, Muju virus, harbored by Myodes regulus in Korea, might represent a genetic variant of Puumala virus, the prototype arvicolid rodent-borne hantavirus.
Lee JG, Gu SH, Baek LJ, Shin OS, Park KS, Kim HC, Klein TA, Yanagihara R, Song JW.

The genome of Muju virus (MUJV), identified originally in the royal vole (Myodes regulus) in Korea, was fully sequenced to ascertain its genetic and phylogenetic relationship with Puumala virus (PUUV), harbored by the bank vole (My. glareolus), and a PUUV-like virus, named Hokkaido virus (HOKV), in …


PLoS One, 2014, The antibody response of pregnant Cameroonian women to VAR2CSA ID1-ID2a, a small recombinant protein containing the CSA-binding site.
Babakhanyan A, Leke RG, Salanti A, Bobbili N, Gwanmesia P, Leke RJ, Quakyi IA, Chen JJ, Taylor DW.

In pregnant women, Plasmodium falciparum-infected erythrocytes expressing the VAR2CSA antigen bind to chondroitin sulfate A in the placenta causing placental malaria. The binding site of VAR2CSA is present in the ID1-ID2a region. This study sought to determine if pregnant Cameroonian women naturally…


PLoS One, 2014, Variable virulence factors in Burkholderia pseudomallei (melioidosis) associated with human disease.
Sarovich DS, Price EP, Webb JR, Ward LM, Voutsinos MY, Tuanyok A, Mayo M, Kaestli M, Currie BJ.

Burkholderia pseudomallei is a Gram-negative environmental bacterium that causes melioidosis, a potentially life-threatening infectious disease affecting mammals, including humans. Melioidosis symptoms are both protean and diverse, ranging from mild, localized skin infections to more severe and ofte…


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Seminars & Events
23 April 2014, 12:00 pm - 1:00 pm
Richard Yanagihara, M.D.

Hantavirus Hunting Beyond the Lamp Post


09 April 2014, 4:00 PM - 5:00 PM
Alexandra Gurary

Flow Cytometry Applications in Research


25 March 2014, 12:00 pm - 3:00 pm
Diane E. Griffin, M.D., Ph.D., Kathryn V. Holmes, Ph.D., Richard J. Kuhn, Ph.D., Jeffrey F. Miller, Ph.D.

2014 COBRE Mini-Symposium


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Workshops
15 March 2013, 1:00 PM - 3:30 PM
Robert Bowers, Ph. D.

Using QIIME for Microbial Community Analysis


13 November 2012, 9:00 AM - 5:00 PM
Pawel Michalak, Ph.D.

RNA-seq


08 November 2012, 1:00 PM
Mirja Wine, Ph.D.

Considerations for Monitoring Immune Cells by Flow Cytometry, Signal Transduction Pathways, Intracellular Proteins, and Tetramers


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Recent Grants
NIH/NIAID, R01AI110769 Mature Virus-like Particles as a New Strategy for Dengue Virus Vaccines
04/01/2014 - 03/31/2019
NIH/NIAID, R21AI105286 Defining Immunity to Placental Malaria using a Multi-assay Predictive Model
03/01/2014 - 02/28/2016
NIH/NIMHD, T37MD008636 International Biomedical Research Training for Hawaiian & Pacific Island Students
12/01/2013 - 11/30/2018
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