Comprising the University of Washington, the University of Michigan, the University of Minnesota and the University of Hawaii at Manoa, the Northern/Pacific Global Health Research Fellows Training Consortium is one of five awardees selected to take part in a prestigious, $20.3-million, five-year pro…

Saguna Verma, an Assistant Professor in the Department of Tropical Medicine, Medical Microbiology and Pharmacology, was an invited speaker at the Keystone Symposium, entitled “Innate Immunity: Sensing the Microbes and Damage Signals”, organized by Gabriel Nunez and Akiko Iwasaki, held on March 4-9, …

Delayed for several years because of failed efforts to secure the necessary $15 million in funds required to match the $32.5 million in grant funds from the National Institute of Allergy and Infectious Diseases, the University of Hawaii is back on track to build a $47.5-million, stand-alone ABSL-3/B…

West Nile virus (WNV) encephalitis is characterized by neuroinflammation, neuronal loss and blood-brain barrier (BBB) disruption. However, the mechanisms associated with the BBB disruption are unclear. Complex interactions between the tight junction proteins (TJP) and the adherens junction proteins …

Recently identified hantaviruses harbored by shrews and moles (order Soricomorpha) suggest that other mammals having shared ancestry may serve as reservoirs. To investigate this possibility, archival tissues from 213 insectivorous bats (order Chiroptera) were analyzed for hantavirus RNA by RT-PCR. F…

BACKGROUND: The envelope (E) protein of dengue virus (DENV) is the major target of neutralizing antibodies and vaccine development. While previous studies on domain III or domain I/II alone have reported several epitopes of monoclonal antibodies (mAbs) against DENV E protein, the possibility of inte…