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News & Research Highlights
20 August 2019: Military Health System Research Symposium
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Former COBRE Small Grants Program awardee, Angel Yanagihara, attended the Military Health System Research Symposium, held in Kissimmee, Florida, on August 19-21 2019, where she presented findings from a collaborative project, entitled “Lethal Box Jellyfish Envenomation Syndromes”, conducted with Cat…


07 December 2018: Efficacy of A Recombinant Subunit Protein-Based Zika Virus Vaccine in Non-human Primates
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Dr. Axel T. Lehrer, a former COBRE Small Grants Program awardee, and his research team have successfully developed a recombinant subunit protein-based vaccine for Zika virus. Previously, he demonstrated that this vaccine was effective in protecting mice from Zika virus challenge. These studies have …


09 November 2018: Stopping the Sting
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The 20-year pursuit of developing effective treatment regimens for box jellyfish envenomation by Angel Yanagihara, a Fulbright Specialist and former COBRE Small Grants Program awardee, is featured in the November 9, 2018 issue of Science.
https://www.sciencemag.org/news/2018/11/jellyfish-almost-kil...


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Recent Publications
Viruses, 2019, Highly divergent genetic variants of soricid-borne Altai virus (Hantaviridae) in Eurasia suggest ancient host-switching events.
Kang HJ, Gu SH, Yashina LN, Cook JA, Yanagihara R.

With the recent discovery of genetically distinct hantaviruses (family Hantaviridae) in shrews (order Eulipotyphla, family Soricidae), the once-conventional view that rodents (order Rodentia) served as the primordial reservoir hosts now appears improbable. The newly identified soricid-borne hantavir…


PLoS Neglected Tropical Diseases, 2019, Serological evidence of Ebola virus exposure in dogs from affected communities in Liberia: a preliminary report.
Haun BK, Kamara V, Dweh AS, Garalde-Machida K, Forkay SSE, Takaaze M, Namekar M, Wong TAS, Bell-Gam Woto AER, Humphreys P, Weeks OI, Fallah MP, Berestecky JM, Nerurkar VR, Lehrer AT.

Filoviruses such as Ebola virus (EBOV) cause outbreaks of viral hemorrhagic fevers for which no FDA-approved vaccines or drugs are available. The 2014-2016 EBOV outbreak in West Africa infected approximately 30,000 people, killing more than 11,000 and affecting thousands more in areas still sufferin…


Viruses, 2019, Complex history of codiversification and host switching of a newfound soricid-borne orthohantavirus in North America.
Liphardt SW, Kang HJ, Dizney LJ, Ruedas LA, Cook JA, Yanagihara R.

Orthohantaviruses are tightly linked to the ecology and evolutionary history of their mammalian hosts. We hypothesized that in regions with dramatic climate shifts throughout the Quaternary, orthohantavirus diversity and evolution are shaped by dynamic host responses to environmental change through …


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Seminars & Events
01 November 2019, 11:00 AM - 12:00 PM
Devan Ray Donaldson, Ph.D.
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Perceptions of Data Quality in Electronic Health Record Reuse


30 October 2019, 12:00 PM - 1:00 PM
Upal Roy, Ph.D.
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HIV Infection of the Brain and Targeted Therapeutic Strategies


30 October 2019, 2:00 PM - 3:00 PM
Tracey Goldstein, Ph.D.
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Ebolavirus Discovery in West Africa


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Workshops
06 June 2019, 10:00 AM
Lisa Bellemare

FLOW CYTOMETRY AND CELL SORTING FOR EVERY TYPE OF BIOLOGICAL SAMPLES


15 February 2019, 9:00 AM - 12:00 PM
Drs. Youping Deng, Mark Menor & Vedbar Khadka

Genome Assembly, Evaluation and Visualization


17 October 2018, 11:00 AM
Bela Desai, Ph.D.

Improving Protein Detection: Accurate, High-Sensitivity and High-Throughput Analysis of Biomarkers


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Recent Grants
Centers for Disease Control, 1 U01GH002256-01 Epidemiology and Immunity to Ebola Virus and Other Emerging Viral Infections in Liberia
09/30/2019 - 09/29/2024
NIH/FIC, 1D71TW010434-01A1 Sustainable Research Training and Capacity Building in Liberia for Emerging Viral Epidemics
09/08/2017 - 08/31/2019
NIH/OD, R21OD024896 A Guinea Pig Model of Zika Virus Disease
09/01/2017 - 08/31/2019
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